Circulating Endothelial Cell an overview

Circulating endothelial cell progenitor cells are thought to continually repair the linings of blood vessels, preventing plaque formation and atherosclerosis The number of circulating endothelial stem cells decreases with age in humans An inverse relationship has been found between the number of circulating EnSCs and risk for cardiovascular

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Circulating Endothelial Cells Circulation

Background Congenital heart disease can be complicated by pulmonary arterial hypertension PAH, the reversibility of which is often difficult to predict We recently reported a lung biopsy study showing impaired apoptotic regulation of endothelial cells in irreversible PAH The objective of the present study was to identify noninvasive bioers of endothelial turnover that could be used

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The multifaceted circulating endothelial cell in cancer

2006 10 5Circulating endothelial cells CECs with a mature phenotype, which are probably derived from blood vessel wall turnover, are increased in patients with some types of

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Circulating Endothelial Cells and Chronic Kidney Disease

2014 2 28Endothelial dysfunction may play a crucial role in initiation of the pathogenesis of vascular disease and atherosclerosis The identification and quantification of circulating endothelial cells CEC have been developed as a novel er of endothelial function We describe, in great detail, mechanisms of endothelial dysfunction and CEC detachment

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Circulating endothelial cells as a er of endothelial

2003 10 17Damage to endothelial cells is the common feature of vascular disorders associated with hematopoietic stem cell transplantation HSCT Elevated numbers of circulating endothelial cells reflect the extent of endothelial damage in a variety of disorders but their use in HSCT has not been investigated so far We studied 39 patients undergoing allogeneic HSCT with different conditioning regimens

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Circulating endothelial cells are an early predictor in

2009 7 7Tyrosine kinase inhibitors TKI have enriched the therapeutic options in patients with renal cell carcinoma RCC, which frequently induce morphological changes in tumors However, only little is known about the biological activity of TKI Circulating endothelial cells CEC have been associated with endothelial damage and, hence, may serve as a putative er for the biological activity of TKI

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Circulating tumor endothelial cell clusters offer

Circulating tumor endothelial cell clusters offer possible colorectal cancer diagnostic By Wanner Circulating tumor cells CTCs in the blood of cancer patients have attracted intense scrutiny because of the potential they offer as easily accessible bioers and indicators of therapeutic response

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Circulating endothelial cell count a reliable er of

2017 9 11Circulating endothelial cell count a reliable er of endothelial damage in patients undergoing hematopoietic stem cell transplantation Skip to

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Circulating Endothelial Cells, Endothelial Progenitor

2014 11 5Cancer, a proliferative disease halled by abnormal cell growth and spread, is largely dependent on tumor neoangiogenesis, with evidence of vascular endothelial dysfunction Novel ways to assess vascular function in cancer include measuring levels of circulating endothelial

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Tumor derived circulating endothelial cell clusters in

rent consensus, we demonstrate that a discrete population of circulating cell clusters isolated from the blood of co lorectalcancer patients are not cancerous but consist of tumor derived endothelial cells These clusters express both epithelial and mesenchymal ers, consistent with prev ious reports on circulating tumor cell CTC phenotyping

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Enumeration of circulating endothelial cell frequency

The frequency of circulating endothelial cells CEC in patients peripheral blood can be assessed as a direct er of endothelial damage However, conventional enumeration methods are extremely challenging We developed a novel, automated approach to determine CEC frequencies and tested this method on two groups of patients undergoing conventional CAVR versus trans catheter aortic valve

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Circulating endothelial progenitor cell a promising

Yu Zheng Ge and Ran Wu have contributed equally to this paper Electronic supplementary material The online version of this article doi 10 1007/s12032 014 0332 x contains supplementary material, which is available to authorized users

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Circulating endothelial cell levels correlate with

2014 4 1Circulating endothelial cell levels correlate with proinflammatory cytokine___ 33 Circulating endothelial cell levels

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CEC,Circulating endothelial cells CEC

2018 10 1Changes in circulating endothelial cell numbers and blood lipid levels and their clinical significance in patients with multiple organ dysfunction syndrome

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Circulating endothelial cells are elevated in patients

However, we know that at least in hyperglycemic states, endothelial cell apoptosis and cell sloughing increase Furthermore, prior studies have demonstrated decreased numbers of bone marrow derived circulating endothelial progenitor cells in conditions associated with endothelial dysfunction 46, 47 Therefore, it is logical to assume that the

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Metformin improves circulating endothelial cells and

Type 1 diabetes is associated with increased cardiovascular disease CVD Decreased endothelial progenitor cells EPCs number plays a pivotal role in reduced endothelial repair and development of CVD We aimed to determine if cardioprotective effect of metformin is mediated by increasing circulating endothelial progenitor cells cEPCs, pro angiogenic cells PACs and decreasing circulating

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Circulating Endothelial Cell Kit Immunomagnetic CTC kit

2018 4 23Circulating Endothelial Cell Kit Immunomagnetic capture and fluorescent staining is intended for the enumeration of circulating tumor cells CTC of epithelial origin CD45 , EpCAM+, and cytokeratins 8, 18+, and/or 19+ in whole blood The presence of CTC in the peripheral blood, as detected by the CellSearch

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PDF Circulating Endothelial Cells, Endothelial

An additional circulating cell population are endothelial progenitor cells EPC, which have the ability to form endothelial colonies in vitro and may contribute toward vasculogenesis

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Circulating Endothelial Progenitor Cells, Vascular

2011 4 16Studies have identified a cell population termed endothelial progenitor cells that can be isolated from circulating mononuclear cells, 1 3 bone marrow, 4 and cord blood 5 Laboratory evidence

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Endothelial progenitor cell

2019 4 23Endothelial progenitor cell or EPC is a term that has been applied to multiple different cell types that play roles in the regeneration of the endothelial lining of blood vessels Outgrowth endothelial cells are an EPC subtype committed to endothelial cell formation Despite the history and controversy, the EPC in all its forms remains a

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CD31labeled circulating endothelial cells as predictor

Studies have shown that compared with the panendothelial cell er CD31, CD105 accurately reflects the proliferation status of endothelial cells 33 35 We believe that CD31 is expressed on all vessels in tumor tissue, while CD105 is predominantly expressed on newly formed blood vessels that are mainly on the frontier infiltration of the

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Circulating endothelial cells, microparticles and

2019 4 2The balance between lesion and regeneration of the endothelium is critical for the maintenance of vessel integrity Exposure to cardiovascular risk factors CRF alters the regulatory functions of the endothelium that progresses from a quiescent state to activation, apoptosis and death In the last 10 years, identification of circulating endothelial cells CEC and endothelial derived

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PDF Circulating endothelial cells Bioer of

Endothelial progenitor cells are a circulating, bone marrow derived cell population of large non leukocyte cells that appears to participate in vascular repair and homeostasis From a theoretical

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Circulating endothelial cell count a reliable er of

2017 9 11Circulating endothelial cell count a reliable er of endothelial damage in patients undergoing hematopoietic stem cell transplantation Skip to

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Tumor derived circulating endothelial cell clusters in

rent consensus, we demonstrate that a discrete population of circulating cell clusters isolated from the blood of co lorectalcancer patients are not cancerous but consist of tumor derived endothelial cells These clusters express both epithelial and mesenchymal ers, consistent with prev ious reports on circulating tumor cell CTC phenotyping

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Circulating tumor endothelial cell clusters offer

Circulating tumor endothelial cell clusters offer possible colorectal cancer diagnostic By Wanner Circulating tumor cells CTCs in the blood of cancer patients have attracted intense scrutiny because of the potential they offer as easily accessible bioers and indicators of therapeutic response

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Tumor derived circulating endothelial cell clusters in

2010 8 4Setting out to isolate circulating tumor cells CTCs in the blood of cancer patients, Cima et al instead noticed that clusters, rather than single cells, were present in their sorting device However, these clusters were not like others reported previously The cells did not express the cell er epithelial cell adhesion molecule EpCAM, and they did not have the same mutations seen in

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Circulating Endothelial Cells as er of Endothelial

Recent studies have established the importance of altered vascular endothelium function in cardiovascular disease The damage to the endothelium might also cause endothelial cell detachment, resulting in increased numbers of circulating endothelial cells CEC within the bloodstream

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Distinct patterns of circulating endothelial cells in

2011 6 14pulmonary arterial pressure and served as controls Circulating endothelial cells were isolated with CD146 coated beads CD34+CD133+ cell and endothelial progenitor cell numbers were respectively determined by flow cytometry and cell culture, in peripheral vein and pulmonary artery blood

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Circulating Endothelial Progenitor Cells and

2017 12 6Circulating endothelial progenitor cells are derived from the bone marrow and are believed to support the integrity of the vascular endothelium Endothelial cell apoptosis biochemical

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Circulating endothelial cells Bioer of vascular

Recent research has recognised new populations of non hematopo2'etic cells in the blood One of these, circulating endothelial cells CECs, often defined by the expression of membrane glycoprotein CD146, are rarely found in the blood in health, but raised numbers are present in a wide variety of human conditions, including inflammatory, immune, infectious, neoplastic and cardiovascular

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Origins of circulating endothelial cells and endothelial

2000 1 1Normal adults have a small number of circulating endothelial cells CEC in peripheral blood, and endothelial outgrowth has been observed from cultures of blood In this study we seek insight into the origins of CEC and endothelial outgrowth from cultures of blood Fluorescence in situ hybridization

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PDF Circulating endothelial cells Bioer of

Endothelial progenitor cells are a circulating, bone marrow derived cell population of large non leukocyte cells that appears to participate in vascular repair and homeostasis From a theoretical

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Circulating endothelial cell

2019 4 4Circulating endothelial cells CECs are endothelial cells that have been shed from the lining of the vascular wall into the blood stream Endothelial cells normally line blood vessels to maintain vascular integrity and permeability, but when these cells enter into the circulation, this could be a reflection of vascular dysfunction and damage There are many factors involved in the process of

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Circulating Endothelial Cells in Cardiovascular Disease

Circulating Endothelial Cells in Cardiovascular Disease Christopher J Boos, Gregory Y H Lip, Andrew D Blann Recent research as identified 2 endothelioid cells in the blood circulating endothelial cells CECs and endothelial progenitor cells EPCs Although a consensual definition of the former is being established and will lead to advances, variation in the characterization of EPCs is

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Circulating endothelial cell kinetics and viability

2017 4 6Circulating endothelial cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy Patrizia Mancuso, Marco Colleoni, Angelica Calleri, Laura Orlando, Patrick Maisonneuve, Giancarlo Pruneri, Alice Agliano, Xinhai Goldhirsch, Yuval Shaked, Robert S Kerbel and Francesco Bertolini

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Circulating tumor endothelial cell clusters offer

Circulating tumor endothelial cell clusters offer possible colorectal cancer diagnostic By Wanner Circulating tumor cells CTCs in the blood of cancer patients have attracted intense scrutiny because of the potential they offer as easily accessible bioers and indicators of therapeutic response

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Circulating endothelial cells life, death, detachment

From a clinician's point of view, CECs are a promising, albeit nonspecific, er of endothelial injury Further study of the cell phenotype may help to elucidate the pathogenesis of some vascular disorders Interactions of circulating necrotic endothelial cells with healthy

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Circulating Endothelial Progenitor Cell Service Services

Abnova Diagnostics provides circulating endothelial progenitor cell EPC service to interested individuals and requesting physicians, clinics, and hospitals Our clinical

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Circulating Endothelial Cells and Circulating

Mancuso P , Calleri A , Bertolini F 2012 Circulating Endothelial Cells and Circulating Endothelial Progenitors In Ignatiadis M , Sotiriou C , Pantel K eds Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer Recent Results in Cancer Research, vol 195 Springer, Berlin, Heidelberg First Online 21 April 2012

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What you need is what we can do!——Yunlong Zhang